PDF DatasheetHuman NR1I3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant NR1I3 based upon sequence from: Human
Host: QP7599 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) NR1I3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7599.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ala2 – Cys351
Amino Acid Sequence: ASREDELRNC VVCGDQATGY HFNALTCEGC KGFFRRTVSK SIGPTCPFAG SCEVSKTQRR HCPACRLQKC LDAGMRKDMI LSAEALALRR AKQAQRRAQQ TPVQLSKEQE ELIRTLLGAH TRHMGTMFEQ FVQFRPPAHL FIHHQPLPTL APVLPLVTHF ADINTFMVLQ VIKFTKDLPV FRSLPIEDQI SLLKGAAVEI CHIVLNTTFC LQTQNFLCGP LRYTIEDGAR VSPTVGFQVE FLELLFHFHG TLRKLQLQEP EYVLLAAMAL FSPDRPGVTQ RDEIDQLQEE MALTLQSYIK GQQRRPRDRF LYAKLLGLLA ELRSINEAYG YQIQHIQGLS AMMPLLQEIC
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human NR1I3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human NR1I3 Protein General Information | |
|---|---|
| Alternate Names | |
| CAR1; CAR; MB67; Nuclear receptor subfamily 1 group I member | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NR1I3 |
| Entrez Gene ID | 9970 |
| Ensemble Gene ID | ENSG00000143257 |
| RefSeq Protein Accession(s) | NP_001070937.1 |
| RefSeq mRNA Accession(s) | NM_001077469.2, NM_001077470.2, NM_001077471.2, NM_001077472.2, NM_001077473.2, NM_001077474.2, NM_001077475.2, NM_001077476.2, NM_001077477.2, NM_001077478.2, NM_001077479.2, NM_001077480.2, NM_001077481.2, NM_001077482.2, NM_005122.4 |
| UniProt ID(s) | Q14994 |
| UniGene ID(s) | Hs.349642 |
| HGNC ID(s) | HGNC:7969 |
| COSMIC ID Link(s) | NR1I3 |
| KEGG Gene ID(s) | hsa:9970 |
| PharmGKB ID(s) | PA391 |
| General Description of Recombinant Human NR1I3 Protein. | |
| Binds and transactivates the retinoic acid response elents that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive elent module of the human CYP2B6 gene and the CYP3A4 xenobiotic response elent. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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