PDF DatasheetHuman CBFB / CBF-beta Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CBFB / CBF-beta based upon sequence from: Human
Host: QP7610 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CBFB / CBF-beta, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7610.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Pro182
Amino Acid Sequence: MPRVVPDQRS KFENEEFFRK LSRECEIKYT GFRDRPHEER QARFQNACRD GRSEIAFVAT GTNLSLQFFP ASWQGEQRQT PSREYVDLER EAGKVYLKAP MILNGVCVIW KGWIDLQRLD GMGCLEFDEE RAQQEDALAQ QAFEEARRRT REFEDRDRSH REEMEVRVSQ LLAVTGKKTT RP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CBFB / CBF-beta Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CBFB / CBF-beta Protein General Information | |
|---|---|
| Alternate Names | |
| CBFB; CBF-beta; PEBP2B | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CBFB |
| Entrez Gene ID | 865 |
| Ensemble Gene ID | ENSG00000067955 |
| RefSeq Protein Accession(s) | NP_001746.1 |
| RefSeq mRNA Accession(s) | NM_001755.2, NM_022845.2 |
| UniProt ID(s) | Q13951 |
| UniGene ID(s) | Hs.460988 |
| HGNC ID(s) | HGNC:1539 |
| COSMIC ID Link(s) | CBFB |
| KEGG Gene ID(s) | hsa:865 |
| PharmGKB ID(s) | PA26114 |
| General Description of Recombinant Human CBFB / CBF-beta Protein. | |
| CBF binds to the core site, 5′-PYGPYGGT-3′, of a number of enhancers and promoters, including murine leukia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBFB enhances DNA binding by RUNX1. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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