PDF DatasheetBovine Agouti-signaling protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Agouti-signaling protein based upon sequence from: Bovine
Host: QP7635 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Bos taurus (Bovine) Agouti-signaling protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7635.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: His23 – Cys133
Amino Acid Sequence: HLAPEEKPRD ERNLKNNSSM NLLDFPSVSI VALNKKSKKI SRNEAEKKKR PSKRKAPMKN VARTRPPPPT PCVATRDSCK PPAPACCDPC AFCQCRFFRS ACSCRVLNPT C
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Bovine Agouti-signaling protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Bovine Agouti-signaling protein Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ASIP |
| Entrez Gene ID | 404192 |
| Ensemble Gene ID | ENSBTAG00000034077 |
| RefSeq Protein Accession(s) | NP_996674.1 |
| RefSeq mRNA Accession(s) | NM_206843.2 |
| UniProt ID(s) | Q29414 |
| UniGene ID(s) | Bt.89130 |
| COSMIC ID Link(s) | ASIP |
| KEGG Gene ID(s) | bta:404192 |
| General Description of Recombinant Bovine Agouti-signaling protein Protein. | |
| Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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