E. coli Cytolethal distending toxin subunit B Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Cytolethal distending toxin subunit B based upon sequence from: E. coli
Host: QP7656 protein expressed in E. coli.
Tag: HIs-Myc
Protein Construction: A DNA sequence encoding the Escherichia coli Cytolethal distending toxin subunit B, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7656.
Bioactivity Data: Untested
Full Length? Full Length of Mature Protein
Expression Region: Asp19 – Arg269
Amino Acid Sequence: DLTDFRVATW NLQGASATTE SKWNINVRQL ISGENAVDIL AVQEAGSPPS TAVDTGTLIP SPGIPVRELI WNLSTNSRPQ QVYIYFSAVD ALGGRVNLAL VSNRRADEVF VLSPVRQGGR PLLGIRIGND AFFTAHAIAM RNNDAPALVE EVYNFFRDSR DPVHQALNWM ILGDFNREPA DLEMNLTVPV RRASEIISPA AATQTSQRTL DYAVAGNSVA FRPSPLQAGI VYGARRTQIS SDHFPVGVSR R
Purity: Greater than 80.40% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of E. coli Cytolethal distending toxin subunit B Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant E. coli Cytolethal distending toxin subunit B Protein General Information | |
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Curated Database and Bioinformatic Data | |
Gene Symbol | cdtB |
UniProt ID(s) | Q46669 |
General Description of Recombinant E. coli Cytolethal distending toxin subunit B Protein. | |
Part of the tripartite complex that is required for the CDT activity. CdtB exhibits a DNA-nicking endonuclease activity, and very probably causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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