PDF DatasheetMouse F-box / WD repeat-containing protein 10 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant F-box / WD repeat-containing protein 10 based upon sequence from: Mouse
Host: QP7709 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) F-box/WD repeat-containing protein 10, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7709.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Val701 – Ile1030
Amino Acid Sequence: VKWQYSSDKN KVKKSKDKEE EREETSLGDE HSRSTIQGHS LKDSVSSKQE FSKSRVHLKQ TKNLSSDDME TPVGEVSHPL QKLWKVPMTP DRFLLTISAL QQAHNSEEFA YPHRPRPQVI DAWGPSIPYP RKVLSLKGKS VQHAVDQLRS SNLPTGVRQT NIPLEIQKLQ PNLKKSLHSP RVQATVPQPS LIRPKVSDSL RGDEHLTSSI DGTMRRAGPL TSMQVIKPNR MLAPRGGTAT LSPKKERPRF YTTLDPLRMN TGFMLMTVKE EKEFAEAKMK EYEASVSTKE VDPGKASKAA WIRKIKGLPI DNFMKEGKTA APELGQNVFI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse F-box / WD repeat-containing protein 10 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse F-box / WD repeat-containing protein 10 Protein General Information | |
|---|---|
| Alternate Names | |
| Fbw10; SM25H2; HREP; SM2SH2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Fbxw10 |
| Ensemble Gene ID | ENSMUSG00000090173 |
| UniProt ID(s) | Q5SUS0 |
| UniGene ID(s) | Mm.482259 |
| COSMIC ID Link(s) | Fbxw10 |
| General Description of Recombinant Mouse F-box / WD repeat-containing protein 10 Protein. | |
| Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1 (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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