PDF DatasheetHuman Autophagy-related protein 16-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Autophagy-related protein 16-1 based upon sequence from: Human
Host: QP7727 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Autophagy-related protein 16-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7727.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Tyr607
Amino Acid Sequence: MSSGLRAADF PRWKRHISEQ LRRRDRLQRQ AFEEIILQYN KLLEKSDLHS VLAQKLQAEK HDVPNRHEIS PGHDGTWNDN QLQEMAQLRI KHQEELTELH KKRGELAQLV IDLNNQMQRK DREMQMNEAK IAECLQTISD LETECLDLRT KLCDLERANQ TLKDEYDALQ ITFTALEGKL RKTTEENQEL VTRWMAEKAQ EANRLNAENE KDSRRRQARL QKELAEAAKE PLPVEQDDDI EVIVDETSDH TEETSPVRAI SRAATKRLSQ PAGGLLDSIT NIFGRRSVSS FPVPQDNVDT HPGSGKEVRV PATALCVFDA HDGEVNAVQF SPGSRLLATG GMDRRVKLWE VFGEKCEFKG SLSGSNAGIT SIEFDSAGSY LLAASNDFAS RIWTVDDYRL RHTLTGHSGK VLSAKFLLDN ARIVSGSHDR TLKLWDLRSK VCIKTVFAGS SCNDIVCTEQ CVMSGHFDKK IRFWDIRSES IVREMELLGK ITALDLNPER TELLSCSRDD LLKVIDLRTN AIKQTFSAPG FKCGSDWTRV VFSPDGSYVA AGSAEGSLYI WSVLTGKVEK VLSKQHSSSI NAVAWSPSGS HVVSVDKGCK AVLWAQY
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Autophagy-related protein 16-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Autophagy-related protein 16-1 Protein General Information | |
|---|---|
| Alternate Names | |
| IBD10; APG16L; ATG16A; ATG16L; WDR30 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ATG16L1 |
| Entrez Gene ID | 55054 |
| Ensemble Gene ID | ENSG00000085978 |
| RefSeq Protein Accession(s) | NP_001177195.1 |
| RefSeq mRNA Accession(s) | NM_001190266.1, NM_001190267.1, NM_017974.3, NM_030803.6, NM_198890.2 |
| UniProt ID(s) | Q676U5 |
| UniGene ID(s) | Hs.529322 |
| HGNC ID(s) | HGNC:21498 |
| COSMIC ID Link(s) | ATG16L1 |
| KEGG Gene ID(s) | hsa:55054 |
| PharmGKB ID(s) | PA134902949 |
| General Description of Recombinant Human Autophagy-related protein 16-1 Protein. | |
| Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a mbrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal mbrane. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.