PDF DatasheetHuman DUSP13, isoform A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant DUSP13, isoform A based upon sequence from: Human
Host: QP7728 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) DUSP13, isoform A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7728.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ser198
Amino Acid Sequence: MAETSLPELG GEDKATPCPS ILELEELLRA GKSSCSRVDE VWPNLFIGDA ATANNRFELW KLGITHVLNA AHKGLYCQGG PDFYGSSVSY LGVPAHDLPD FDISAYFSSA ADFIHRALNT PGAKVLVHCV VGVSRSATLV LAYLMLHQRL SLRQAVITVR QHRWVFPNRG FLHQLCRLDQ QLRGAGQS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human DUSP13, isoform A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human DUSP13, isoform A Protein General Information | |
|---|---|
| Alternate Names | |
| BEDP; DUSP13B; MDSP; SKRP4; TMDP; DUSP13A; Dual specificity protein phosphatase 13 isoform | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DUSP13 |
| Entrez Gene ID | 51207 |
| Ensemble Gene ID | ENSG00000079393 |
| RefSeq Protein Accession(s) | NP_001007272.1 |
| RefSeq mRNA Accession(s) | NM_001007271.1, NM_001007272.1, NM_001007273.1, NM_001320842.1, NM_001320843.1 |
| UniProt ID(s) | Q6B8I1 |
| UniGene ID(s) | Hs.178170 |
| HGNC ID(s) | HGNC:19681 |
| COSMIC ID Link(s) | DUSP13 |
| KEGG Gene ID(s) | hsa:51207 |
| PharmGKB ID(s) | PA134939640 |
| General Description of Recombinant Human DUSP13, isoform A Protein. | |
| Probable protein tyrosine phosphatase. Has a phosphatase activity-independent regulatory role in MAP3K5/ASK1-mediated apoptosis, preventing MAP3K5/ASK1 inhibition by AKT1. Shows no phosphatase activity on MAPK1/ERK2, MAPK8/JNK, MAPK14/p38 and MAP3K5/ASK1. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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