PDF DatasheetHuman Vasohibin-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Vasohibin-1 based upon sequence from: Human
Isoform: Isoform 2
Host: QP7744 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Vasohibin-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7744.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 2
Expression Region: Met1 – Gly204
Amino Acid Sequence: MPGGKKVAGG GSSGATPTSA AATAPSGVRR LETSEGTSAQ RDEEPEEEGE EDLRDGGVPF FVNRGGLPVD EATWERMWKH VAKIHPDGEK VAQRIRGATD LPKIPIPSVP TFQPSTPVPE RLEAVQRYIR ELQYNHTGTQ FFEIKKSRPL TGLMDLAKEM TKEALPIKCL EAVILGMYPS SPEGEGSGLL WASASCSESE GGVG
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Vasohibin-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Vasohibin-1 Protein General Information | |
|---|---|
| Alternate Names | |
| KIAA1036 | |
| Molecular Weight | |
| Isoform 2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | VASH1 |
| Entrez Gene ID | 22846 |
| Ensemble Gene ID | ENSG00000071246 |
| RefSeq Protein Accession(s) | NP_055724.1 |
| RefSeq mRNA Accession(s) | NM_014909.4 |
| UniProt ID(s) | Q7L8A9 |
| UniGene ID(s) | Hs.525479 |
| HGNC ID(s) | HGNC:19964 |
| COSMIC ID Link(s) | VASH1 |
| KEGG Gene ID(s) | hsa:22846 |
| PharmGKB ID(s) | PA134941450 |
| General Description of Recombinant Human Vasohibin-1 Protein. | |
| Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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