PDF DatasheetHuman DNA oxidative demethylase ALKBH2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant DNA oxidative demethylase ALKBH2 based upon sequence from: Human
Host: QP7771 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) DNA oxidative demethylase ALKBH2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7771.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: MDRFLVKGAQ GGLLRKQEEQ EPTGEEPAVL GGDKESTRKR PRREAPGNGG HSAGPSWRHI RAEGLDCSYT VLFGKAEADE IFQELEKEVE YFTGALARVQ VFGKWHSVPR KQATYGDAGL TYTFSGLTLS PKPWIPVLER IRDHVSGVTG QTFNFVLINR YKDGCDHIGE HRDDERELAP GSPIASVSFG ACRDFVFRHK DSRGKSPSRR VAVVRLPLAH GSLLMMNHPT NTHWYHSLPV RKKVLAPRVN LTFRKILLTK K
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human DNA oxidative demethylase ALKBH2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human DNA oxidative demethylase ALKBH2 Protein General Information | |
|---|---|
| Alternate Names | |
| ABH2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ALKBH2 |
| Entrez Gene ID | 121642 |
| Ensemble Gene ID | ENSG00000189046 |
| RefSeq Protein Accession(s) | NP_001001655.1 |
| RefSeq mRNA Accession(s) | NM_001001655.2, NM_001145374.1, NM_001145375.1, NM_001205179.1, NM_001205180.1, XM_005253835.4, XM_005253836.1 |
| UniProt ID(s) | Q6NS38 |
| UniGene ID(s) | Hs.374458 |
| HGNC ID(s) | HGNC:32487 |
| COSMIC ID Link(s) | ALKBH2 |
| KEGG Gene ID(s) | hsa:121642 |
| PharmGKB ID(s) | PA143485292 |
| General Description of Recombinant Human DNA oxidative demethylase ALKBH2 Protein. | |
| Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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