PDF DatasheetHuman NET1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant NET1 based upon sequence from: Human
Isoform: Isoform 2
Host: QP7782 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) NET1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7782.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 2
Expression Region: Met1 – Val542
Amino Acid Sequence: MVAHDETGGL LPIKRTIRVL DVNNQSFREQ EEPSNKRVRP LARVTSLANL ISPVRNGAVR RFGQTIQSFT LRGDHRSPAS AQKFSSRSTV PTPAKRRSSA LWSEMLDITM KESLTTREIR RQEAIYEMSR GEQDLIEDLK LARKAYHDPM LKLSIMSEEE LTHIFGDLDS YIPLHEDLLT RIGEATKPDG TVEQIGHILV SWLPRLNAYR GYCSNQLAAK ALLDQKKQDP RVQDFLQRCL ESPFSRKLDL WSFLDIPRSR LVKYPLLLKE ILKHTPKEHP DVQLLEDAIL IIQGVLSDIN LKKGESECQY YIDKLEYLDE KQRDPRIEAS KVLLCHGELR SKSGHKLYIF LFQDILVLTR PVTRNERHSY QVYRQPIPVQ ELVLEDLQDG DVRMGGSFRG AFSNSEKAKN IFRIRFHDPS PAQSHTLQAN DVFHKQQWFN CIRAAIAPFQ SAGSPPELQG LPELHEECEG NHPSARKLTA QRRASTVSSV TQVEVDENAY RCGSGMQMAE DSKSLKTHQT QPGIRRARDK ALSGGKRKET LV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human NET1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human NET1 Protein General Information | |
|---|---|
| Alternate Names | |
| ARHGEF8; NET1A; Neuroepithelial cell-transforming gene 1 prote | |
| Molecular Weight | |
| Isoform 2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NET1 |
| Entrez Gene ID | 10276 |
| Ensemble Gene ID | ENSG00000173848 |
| RefSeq Protein Accession(s) | NP_001040625.1 |
| RefSeq mRNA Accession(s) | NM_001047160.2, NM_005863.4 |
| UniProt ID(s) | Q7Z628 |
| UniGene ID(s) | Hs.25155 |
| HGNC ID(s) | HGNC:14592 |
| COSMIC ID Link(s) | NET1 |
| KEGG Gene ID(s) | hsa:10276 |
| PharmGKB ID(s) | PA164742175 |
| General Description of Recombinant Human NET1 Protein. | |
| Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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