PDF DatasheetHuman Src kinase-associated phosphoprotein 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Src kinase-associated phosphoprotein 1 based upon sequence from: Human
Host: QP7785 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Src kinase-associated phosphoprotein 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7785.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Glu358
Amino Acid Sequence: MQAAALPEEI RWLLEDAEEF LAEGLRNENL SAVARDHRDH ILRGFQQIKA RYYWDFQPQG GDIGQDSSDD NHSGTLGLSL TSDAPFLSDY QDEGMEDIVK GAQELDNVIK QGYLEKKSKD HSFFGSEWQK RWCVVSRGLF YYYANEKSKQ PKGTFLIKGY GVRMAPHLRR DSKKESCFEL TSQDRRSYEF TATSPAEARD WVDQISFLLK DLSSLTIPYE EDEEEEEKEE TYDDIDGFDS PSCGSQCRPT ILPGSVGIKE PTEEKEEEDI YEVLPDEEHD LEEDESGTRR KGVDYASYYQ GLWDCHGDQP DELSFQRGDL IRILSKEYNM YGWWVGELNS LVGIVPKEYL TTAFEVEE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Src kinase-associated phosphoprotein 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Src kinase-associated phosphoprotein 1 Protein General Information | |
|---|---|
| Alternate Names | |
| SCAP1; HEL-S-81p; SKAP55 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SKAP1 |
| Entrez Gene ID | 8631 |
| Ensemble Gene ID | ENSG00000141293 |
| RefSeq Protein Accession(s) | NP_001068567.1 |
| RefSeq mRNA Accession(s) | NM_001075099.1, NM_003726.3 |
| UniProt ID(s) | Q86WV1 |
| UniGene ID(s) | Hs.316931 |
| HGNC ID(s) | HGNC:15605 |
| COSMIC ID Link(s) | SKAP1 |
| KEGG Gene ID(s) | hsa:8631 |
| PharmGKB ID(s) | PA162403362 |
| General Description of Recombinant Human Src kinase-associated phosphoprotein 1 Protein. | |
| Positively regulates T-cell receptor signaling by enhancing the MAP kinase pathway. Required for optimal conjugation between T-cells and antigen-presenting cells by promoting the clustering of integrin ITGAL on the surface of T-cells. May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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