PDF DatasheetHuman DCXR / HCR2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant DCXR / HCR2 based upon sequence from: Human
Host: QP7792 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) DCXR / HCR2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7792.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Cys244
Amino Acid Sequence: MELFLAGRRV LVTGAGKGIG RGTVQALHAT GARVVAVSRT QADLDSLVRE CPGIEPVCVD LGDWEATERA LGSVGPVDLL VNNAAVALLQ PFLEVTKEAF DRSFEVNLRA VIQVSQIVAR GLIARGVPGA IVNVSSQCSQ RAVTNHSVYC STKGALDMLT KVMALELGPH KIRVNAVNPT VVMTSMGQAT WSDPHKAKTM LNRIPLGKFA EVEHVVNAIL FLLSDRSGMT TGSTLPVEGG FWAC
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human DCXR / HCR2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human DCXR / HCR2 Protein General Information | |
|---|---|
| Alternate Names | |
| DCXR; HCR2; DCR; HCRII; HCR2; P34H; SDR20C1; XR; PNTSU; KIDCR | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DCXR |
| Entrez Gene ID | 51181 |
| Ensemble Gene ID | ENSG00000169738 |
| RefSeq Protein Accession(s) | NP_001182147.1 |
| RefSeq mRNA Accession(s) | NM_001195218.1, NM_016286.3 |
| UniProt ID(s) | Q7Z4W1 |
| UniGene ID(s) | Hs.9857 |
| HGNC ID(s) | HGNC:18985 |
| COSMIC ID Link(s) | DCXR |
| KEGG Gene ID(s) | hsa:51181 |
| PharmGKB ID(s) | PA38772 |
| General Description of Recombinant Human DCXR / HCR2 Protein. | |
| Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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