PDF DatasheetHuman CHD1L Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CHD1L based upon sequence from: Human
Host: QP7802 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CHD1L, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7802.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser704 – Pro897
Amino Acid Sequence: SAELDYQDPD ATSLKYVSGD VTHPQAGAED ALIVHCVDDS GHWGRGGLFT ALEKRSAEPR KIYELAGKMK DLSLGGVLLF PVDDKESRNK GQDLLALIVA QHRDRSNVLS GIKMAALEEG LKKIFLAAKK KKASVHLPRI GHATKGFNWY GTERLIRKHL AARGIPTYIY YFPRSKSAVL HAQSSSSSSR QLVP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CHD1L Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CHD1L Protein General Information | |
|---|---|
| Alternate Names | |
| CHDL; ALC1; Chromodomain-helicase-DNA-binding protein 1-li | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CHD1L |
| Entrez Gene ID | 9557 |
| Ensemble Gene ID | ENSG00000131778 |
| RefSeq Protein Accession(s) | NP_001243267.1 |
| RefSeq mRNA Accession(s) | NM_001256338.2, NM_004284.5 |
| UniProt ID(s) | Q86WJ1 |
| UniGene ID(s) | Hs.191164 |
| HGNC ID(s) | HGNC:1916 |
| COSMIC ID Link(s) | CHD1L |
| KEGG Gene ID(s) | hsa:9557 |
| PharmGKB ID(s) | PA26452 |
| General Description of Recombinant Human CHD1L Protein. | |
| DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.