PDF DatasheetHuman Sentrin-specific protease 8 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Sentrin-specific protease 8 based upon sequence from: Human
Host: QP7846 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Sentrin-specific protease 8, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7846.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Lys212
Amino Acid Sequence: MDPVVLSYMD SLLRQSDVSL LDPPSWLNDH IIGFAFEYFA NSQFHDCSDH VSFISPEVTQ FIKCTSNPAE IAMFLEPLDL PNKRVVFLAI NDNSNQAAGG THWSLLVYLQ DKNSFFHYDS HSRSNSVHAK QVAEKLEAFL GRKGDKLAFV EEKAPAQQNS YDCGMYVICN TEALCQNFFR QQTESLLQLL TPAYITKKRG EWKDLITTLA KK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Sentrin-specific protease 8 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Sentrin-specific protease 8 Protein General Information | |
|---|---|
| Alternate Names | |
| PRSC2; NEDP1; DEN1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SENP8 |
| Entrez Gene ID | 123228 |
| Ensemble Gene ID | ENSG00000166192 |
| RefSeq Protein Accession(s) | NP_001159812.1 |
| RefSeq mRNA Accession(s) | NM_001166340.1, NM_001172109.1, NM_001172110.1, NM_001172111.1, NM_145204.3, XM_005254157.3, XM_011521217.2 |
| UniProt ID(s) | Q96LD8 |
| UniGene ID(s) | Hs.513002 |
| HGNC ID(s) | HGNC:22992 |
| COSMIC ID Link(s) | SENP8 |
| KEGG Gene ID(s) | hsa:123228 |
| PharmGKB ID(s) | PA134866772 |
| General Description of Recombinant Human Sentrin-specific protease 8 Protein. | |
| Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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