PDF DatasheetHuman RCHY1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant RCHY1 based upon sequence from: Human
Host: QP7847 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) RCHY1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7847.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Gln261
Amino Acid Sequence: MAATAREDGA SGQERGQRGC EHYDRGCLLK APCCDKLYTC RLCHDNNEDH QLDRFKVKEV QCINCEKIQH AQQTCEECST LFGEYYCDIC HLFDKDKKQY HCENCGICRI GPKEDFFHCL KCNLCLAMNL QGRHKCIENV SRQNCPICLE DIHTSRVVAH VLPCGHLLHR TCYEEMLKEG YRCPLCMHSA LDMTRYWRQL DDEVAQTPMP SEYQNMTVDI LCNDCNGRST VQFHILGMKC KICESYNTAQ AGGRRISLDQ Q
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human RCHY1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human RCHY1 Protein General Information | |
|---|---|
| Alternate Names | |
| ZCHY; ARNIP; ZNF363; PRO1996; PIRH2; RNF199; CHIMP; RING finger and CHY zinc finger domain-containing protein | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RCHY1 |
| Entrez Gene ID | 25898 |
| Ensemble Gene ID | ENSG00000163743 |
| RefSeq Protein Accession(s) | NP_001009922.1 |
| RefSeq mRNA Accession(s) | NM_001009922.2, NM_001278536.1, NM_001278537.1, NM_001278538.1, NM_015436.3 |
| UniProt ID(s) | Q96PM5 |
| UniGene ID(s) | Hs.48297 |
| HGNC ID(s) | HGNC:17479 |
| COSMIC ID Link(s) | RCHY1 |
| KEGG Gene ID(s) | hsa:25898 |
| PharmGKB ID(s) | PA38240 |
| General Description of Recombinant Human RCHY1 Protein. | |
| Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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