Human DRAXIN Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant DRAXIN based upon sequence from: Human
Host: QP7855 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) DRAXIN, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7855.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly26 – Val349
Amino Acid Sequence: GALAPGTPAR NLPENHIDLP GPALWTPQAS HHRRRGPGKK EWGPGLPSQA QDGAVVTATR QASRLPEAEG LLPEQSPAGL LQDKDLLLGL ALPYPEKENR PPGWERTRKR SREHKRRRDR LRLHQGRALV RGPSSLMKKA ELSEAQVLDA AMEESSTSLA PTMFFLTTFE AAPATEESLI LPVTSLRPQQ AQPRSDGEVM PTLDMALFDW TDYEDLKPDG WPSAKKKEKH RGKLSSDGNE TSPAEGEPCD HHQDCLPGTC CDLREHLCTP HNRGLNNKCF DDCMCVEGLR CYAKFHRNRR VTRRKGRCVE PETANGDQGS FINV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human DRAXIN Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human DRAXIN Protein General Information | |
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Alternate Names | |
DRAXIN; AGPA3119; neucrin; C1orf187; UNQ3119 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | DRAXIN |
Entrez Gene ID | 374946 |
Ensemble Gene ID | ENSG00000162490 |
RefSeq Protein Accession(s) | NP_940947.3 |
RefSeq mRNA Accession(s) | NM_198545.3 |
UniProt ID(s) | Q8NBI3 |
UniGene ID(s) | Hs.632364 |
HGNC ID(s) | HGNC:25054 |
KEGG Gene ID(s) | hsa:374946 |
PharmGKB ID(s) | PA142672435 |
General Description of Recombinant Human DRAXIN Protein. | |
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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