PDF DatasheetHuman DENN domain-containing protein 1A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant DENN domain-containing protein 1A based upon sequence from: Human
Isoform: Isoform 2
Host: QP7858 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) DENN domain-containing protein 1A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7858.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 2
Expression Region: Met1 – His559
Amino Acid Sequence: MGSRIKQNPE TTFEVYVEVA YPRTGGTLSD PEVQRQFPED YSDQEVLQTL TKFCFPFYVD SLTVSQVGQN FTFVLTDIDS KQRFGFCRLS SGAKSCFCIL SYLPWFEVFY KLLNILADYT TKRQENQWNE LLETLHKLPI PDPGVSVHLS VHSYFTVPDT RELPSIPENR NLTEYFVAVD VNNMLHLYAS MLYERRILII CSKLSTLTAC IHGSAAMLYP MYWQHVYIPV LPPHLLDYCC APMPYLIGIH LSLMEKVRNM ALDDVVILNV DTNTLETPFD DLQSLPNDVI SSLKNRLKKV STTTGDGVAR AFLKAQAAFF GSYRNALKIE PEEPITFCEE AFVSHYRSGA MRQFLQNATQ LQLFKQFIDG RLDLLNSGEG FSDVFEEEIN MGEYAGSDKL YHQWLSTVRK GSGAILNTVK TKANPAMKTV YKFAKDHAKM GIKEVKNRLK QKDIAENGCA PTPEEQLPKT APSPLVEAKD PKLREDRRPI TVHFGQVRPP RPHVVKRPKS NIAVEGRRTS VPSPEQNTIA TPATLHILQK SITHFAAKFP TRGWTSSSH
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human DENN domain-containing protein 1A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human DENN domain-containing protein 1A Protein General Information | |
|---|---|
| Alternate Names | |
| FAM31A; KIAA1608 | |
| Molecular Weight | |
| Isoform 2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DENND1A |
| Entrez Gene ID | 57706 |
| Ensemble Gene ID | ENSG00000119522 |
| RefSeq Protein Accession(s) | NP_065997.1 |
| RefSeq mRNA Accession(s) | NM_020946.1, NM_024820.2 |
| UniProt ID(s) | Q8TEH3 |
| UniGene ID(s) | Hs.744995 |
| HGNC ID(s) | HGNC:29324 |
| COSMIC ID Link(s) | DENND1A |
| KEGG Gene ID(s) | hsa:57706 |
| PharmGKB ID(s) | PA134876117 |
| General Description of Recombinant Human DENN domain-containing protein 1A Protein. | |
| Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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