PDF DatasheetHuman U7 snRNA-associated Sm-like protein LSm10 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant U7 snRNA-associated Sm-like protein LSm10 based upon sequence from: Human
Host: QP7867 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) U7 snRNA-associated Sm-like protein LSm10, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7867.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Lys123
Amino Acid Sequence: MAVSHSVKER TISENSLIIL LQGLQGRVTT VDLRDESVAH GRIDNVDAFM NIRLAKVTYT DRWGHQVKLD DLFVTGRNVR YVHIPDDVNI TSTIEQQLQI IHRVRNFGGK GQGRWEFPPK NCK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human U7 snRNA-associated Sm-like protein LSm10 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human U7 snRNA-associated Sm-like protein LSm10 Protein General Information | |
|---|---|
| Alternate Names | |
| MSTP074; MST074 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | LSM10 |
| Entrez Gene ID | 84967 |
| Ensemble Gene ID | ENSG00000181817 |
| RefSeq Protein Accession(s) | NP_116270.1 |
| RefSeq mRNA Accession(s) | NM_032881.2 |
| UniProt ID(s) | Q969L4 |
| UniGene ID(s) | Hs.603131 |
| HGNC ID(s) | HGNC:17562 |
| COSMIC ID Link(s) | LSM10 |
| KEGG Gene ID(s) | hsa:84967 |
| PharmGKB ID(s) | PA134977215 |
| General Description of Recombinant Human U7 snRNA-associated Sm-like protein LSm10 Protein. | |
| Appears to function in the U7 snRNP complex that is involved in histone 3′-end processing. Increases U7 snRNA levels but not histone 3′-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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