PDF DatasheetHuman PNPLA2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant PNPLA2 based upon sequence from: Human
Host: QP7868 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) PNPLA2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7868.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Leu504
Amino Acid Sequence: MFPREKTWNI SFAGCGFLGV YYVGVASCLR EHAPFLVANA THIYGASAGA LTATALVTGV CLGEAGAKFI EVSKEARKRF LGPLHPSFNL VKIIRSFLLK VLPADSHEHA SGRLGISLTR VSDGENVIIS HFNSKDELIQ ANVCSGFIPV YCGLIPPSLQ GVRYVDGGIS DNLPLYELKN TITVSPFSGE SDICPQDSST NIHELRVTNT SIQFNLRNLY RLSKALFPPE PLVLREMCKQ GYRDGLRFLQ RNGLLNRPNP LLALPPARPH GPEDKDQAVE SAQAEDYSQL PGEDHILEHL PARLNEALLE ACVEPTDLLT TLSNMLPVRL ATAMMVPYTL PLESALSFTI RLLEWLPDVP EDIRWMKEQT GSICQYLVMR AKRKLGRHLP SRLPEQVELR RVQSLPSVPL SCAAYREALP GWMRNNLSLG DALAKWEECQ RQLLLGLFCT NVAFPPEALR MRAPADPAPA PADPASPQHQ LAGPAPLLST PAPEARPVIG ALGL
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human PNPLA2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human PNPLA2 Protein General Information | |
|---|---|
| Alternate Names | |
| ATGL; FP17548; TTS2; iPLA2zeta; PEDF-R; TTS-2.2; 1110001C14Rik; Patatin-like phospholipase domain-containing protein | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PNPLA2 |
| Entrez Gene ID | 57104 |
| Ensemble Gene ID | ENSG00000177666 |
| RefSeq Protein Accession(s) | NP_065109.1 |
| RefSeq mRNA Accession(s) | NM_020376.3, XM_017018028.1 |
| UniProt ID(s) | Q96AD5 |
| UniGene ID(s) | Hs.654697 |
| HGNC ID(s) | HGNC:30802 |
| COSMIC ID Link(s) | PNPLA2 |
| KEGG Gene ID(s) | hsa:57104 |
| PharmGKB ID(s) | PA134903083 |
| General Description of Recombinant Human PNPLA2 Protein. | |
| Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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