Mouse CD207 / Langerin Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CD207 / Langerin based upon sequence from: Mouse
Host: QP7887 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) CD207 / Langerin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7887.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Gln63 – Glu331
Amino Acid Sequence: QAVFYPRLMG KILDVKSDAQ MLKGRVDNIS TLGSDLKTER GRVDDAEVQM QIVNTTLKRV RSQILSLETS MKIANDQLQI LTMSWGEVDS LSAKIPELKR DLDKASALNT KVQGLQNSLE NVNKLLKQQS DILEMVARGW KYFSGNFYYF SRTPKTWYSA EQFCISRKAH LTSVSSESEQ KFLYKAADGI PHWIGLTKAG SEGDWYWVDQ TSFNKEQSRR FWIPGEPNNA GNNEHCANIR VSALKCWNDG PCDNTFLFIC KRPYVQTTE
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse CD207 / Langerin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Mouse CD207 / Langerin Protein General Information | |
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Curated Database and Bioinformatic Data | |
Gene Symbol | Cd207 |
Entrez Gene ID | 246278 |
Ensemble Gene ID | ENSMUSG00000034783 |
RefSeq Protein Accession(s) | NP_659192.2 |
RefSeq mRNA Accession(s) | NM_144943.3 |
UniProt ID(s) | Q8VBX4 |
UniGene ID(s) | Mm.136079 |
COSMIC ID Link(s) | Cd207 |
KEGG Gene ID(s) | mmu:246278 |
General Description of Recombinant Mouse CD207 / Langerin Protein. | |
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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