PDF DatasheetHuman Methylthioribulose-1-phosphate dehydratase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Methylthioribulose-1-phosphate dehydratase based upon sequence from: Human
Host: QP7896 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Methylthioribulose-1-phosphate dehydratase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7896.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Val242
Amino Acid Sequence: MSGCDAREGD CCSRRCGAQD KEHPRYLIPE LCKQFYHLGW VTGTGGGISL KHGDEIYIAP SGVQKERIQP EDMFVCDINE KDISGPSPSK KLKKSQCTPL FMNAYTMRGA GAVIHTHSKA AVMATLLFPG REFKITHQEM IKGIKKCTSG GYYRYDDMLV VPIIENTPEE KDLKDRMAHA MNEYPDSCAV LVRRHGVYVW GETWEKAKTM CECYDYLFDI AVSMKKVGLD PSQLPVGENG IV
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Methylthioribulose-1-phosphate dehydratase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Methylthioribulose-1-phosphate dehydratase Protein General Information | |
|---|---|
| Alternate Names | |
| hAPIP; CGI-29; MMRP19; APIP2; CGI29 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | APIP |
| Entrez Gene ID | 51074 |
| Ensemble Gene ID | ENSG00000149089 |
| RefSeq Protein Accession(s) | NP_057041.2 |
| RefSeq mRNA Accession(s) | NM_015957.3 |
| UniProt ID(s) | Q96GX9 |
| UniGene ID(s) | Hs.447794 |
| HGNC ID(s) | HGNC:17581 |
| COSMIC ID Link(s) | APIP |
| KEGG Gene ID(s) | hsa:51074 |
| PharmGKB ID(s) | PA142672601 |
| General Description of Recombinant Human Methylthioribulose-1-phosphate dehydratase Protein. | |
| Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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