PDF DatasheetHuman AADAT Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant AADAT based upon sequence from: Human
Host: QP7920 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) AADAT, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7920.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Pro30 – Leu425
Amino Acid Sequence: PKSMISLAGG LPNPNMFPFK TAVITVENGK TIQFGEEMMK RALQYSPSAG IPELLSWLKQ LQIKLHNPPT IHYPPSQGQM DLCVTSGSQQ GLCKVFEMII NPGDNVLLDE PAYSGTLQSL HPLGCNIINV ASDESGIVPD SLRDILSRWK PEDAKNPQKN TPKFLYTVPN GNNPTGNSLT SERKKEIYEL ARKYDFLIIE DDPYYFLQFN KFRVPTFLSM DVDGRVIRAD SFSKIISSGL RIGFLTGPKP LIERVILHIQ VSTLHPSTFN QLMISQLLHE WGEEGFMAHV DRVIDFYSNQ KDAILAAADK WLTGLAEWHV PAAGMFLWIK VKGINDVKEL IEEKAVKMGV LMLPGNAFYV DSSAPSPYLR ASFSSASPEQ MDVAFQVLAQ LIKESL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human AADAT Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human AADAT Protein General Information | |
|---|---|
| Alternate Names | |
| KAT2; KATII; KYAT2; Kynurenine/alpha-aminoadipate aminotransferase, mitochondri | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | AADAT |
| Entrez Gene ID | 51166 |
| Ensemble Gene ID | ENSG00000109576 |
| RefSeq Protein Accession(s) | NP_001273611.1 |
| RefSeq mRNA Accession(s) | NM_001286682.1, NM_001286683.1, NM_016228.3, NM_182662.1 |
| UniProt ID(s) | Q8N5Z0 |
| UniGene ID(s) | Hs.529735 |
| HGNC ID(s) | HGNC:17929 |
| COSMIC ID Link(s) | AADAT |
| KEGG Gene ID(s) | hsa:51166 |
| PharmGKB ID(s) | PA24364 |
| General Description of Recombinant Human AADAT Protein. | |
| Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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