PDF DatasheetHuman Estradiol 17-beta-dehydrogenase 11 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Estradiol 17-beta-dehydrogenase 11 based upon sequence from: Human
Host: QP7921 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Estradiol 17-beta-dehydrogenase 11, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7921.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu20 – Gln300
Amino Acid Sequence: ESFVKLFIPK RRKSVTGEIV LITGAGHGIG RLTAYEFAKL KSKLVLWDIN KHGLEETAAK CKGLGAKVHT FVVDCSNRED IYSSAKKVKA EIGDVSILVN NAGVVYTSDL FATQDPQIEK TFEVNVLAHF WTTKAFLPAM TKNNHGHIVT VASAAGHVSV PFLLAYCSSK FAAVGFHKTL TDELAALQIT GVKTTCLCPN FVNTGFIKNP STSLGPTLEP EEVVNRLMHG ILTEQKMIFI PSSIAFLTTL ERILPERFLA VLKQKISVKF DAVIGYKMKA Q
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Estradiol 17-beta-dehydrogenase 11 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Estradiol 17-beta-dehydrogenase 11 Protein General Information | |
|---|---|
| Alternate Names | |
| 17BHSD11; PAN1B; 17-BETA-HSDXI; DHRS8; SDR16C2; 17-BETA-HSD11; RETSDR2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HSD17B11 |
| Entrez Gene ID | 51170 |
| Ensemble Gene ID | ENSG00000198189 |
| RefSeq Protein Accession(s) | NP_057329.3 |
| RefSeq mRNA Accession(s) | NM_016245.4 |
| UniProt ID(s) | Q8NBQ5 |
| UniGene ID(s) | Hs.594923 |
| HGNC ID(s) | HGNC:22960 |
| COSMIC ID Link(s) | HSD17B11 |
| KEGG Gene ID(s) | hsa:51170 |
| PharmGKB ID(s) | PA162391655 |
| General Description of Recombinant Human Estradiol 17-beta-dehydrogenase 11 Protein. | |
| Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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