PDF DatasheetHuman SCARB1 / CD36L1 / CLA-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant SCARB1 / CD36L1 / CLA-1 based upon sequence from: Human
Host: QP7926 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) SCARB1 / CD36L1 / CLA-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7926.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Pro33 – Tyr443
Amino Acid Sequence: PSLIKQQVLK NVRIDPSSLS FNMWKEIPIP FYLSVYFFDV MNPSEILKGE KPQVRERGPY VYREFRHKSN ITFNNNDTVS FLEYRTFQFQ PSKSHGSESD YIVMPNILVL GAAVMMENKP MTLKLIMTLA FTTLGERAFM NRTVGEIMWG YKDPLVNLIN KYFPGMFPFK DKFGLFAELN NSDSGLFTVF TGVQNISRIH LVDKWNGLSK VDFWHSDQCN MINGTSGQMW PPFMTPESSL EFYSPEACRS MKLMYKESGV FEGIPTYRFV APKTLFANGS IYPPNEGFCP CLESGIQNVS TCRFSAPLFL SHPHFLNADP VLAEAVTGLH PNQEAHSLFL DIHPVTGIPM NCSVKLQLSL YMKSVAGIGQ TGKIEPVVLP LLWFAESGAM EGETLHTFYT QLVLMPKVMH Y
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human SCARB1 / CD36L1 / CLA-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human SCARB1 / CD36L1 / CLA-1 Protein General Information | |
|---|---|
| Alternate Names | |
| SCARB1; CD36L1; CLA-1; AI120173; Cd36l1; Cla-1; SR-BI; Hlb398; Cla1; Hdlq1; D5Ertd460e; SRBI; mSR-BI; CD36; SR-B1; Chohd1; Srb1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SCARB1 |
| Entrez Gene ID | 949 |
| Ensemble Gene ID | ENSG00000073060 |
| RefSeq Protein Accession(s) | NP_001076428.1 |
| RefSeq mRNA Accession(s) | NM_001082959.1, NM_005505.4 |
| UniProt ID(s) | Q8WTV0 |
| UniGene ID(s) | Hs.731377 |
| HGNC ID(s) | HGNC:1664 |
| COSMIC ID Link(s) | SCARB1 |
| KEGG Gene ID(s) | hsa:949 |
| PharmGKB ID(s) | PA97 |
| General Description of Recombinant Human SCARB1 / CD36L1 / CLA-1 Protein. | |
| Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma mbrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and Extracellular domain donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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