PDF DatasheetHuman Protein atonal homolog 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Protein atonal homolog 1 based upon sequence from: Human
Host: QP7932 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Protein atonal homolog 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7932.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ser354
Amino Acid Sequence: MSRLLHAEEW AEVKELGDHH RQPQPHHLPQ PPPPPQPPAT LQAREHPVYP PELSLLDSTD PRAWLAPTLQ GICTARAAQY LLHSPELGAS EAAAPRDEVD GRGELVRRSS GGASSSKSPG PVKVREQLCK LKGGVVVDEL GCSRQRAPSS KQVNGVQKQR RLAANARERR RMHGLNHAFD QLRNVIPSFN NDKKLSKYET LQMAQIYINA LSELLQTPSG GEQPPPPPAS CKSDHHHLRT AASYEGGAGN ATAAGAQQAS GGSQRPTPPG SCRTRFSAPA SAGGYSVQLD ALHFSTFEDS ALTAMMAQKN LSPSLPGSIL QPVQEENSKT SPRSHRSDGE FSPHSHYSDS DEAS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Protein atonal homolog 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Protein atonal homolog 1 Protein General Information | |
|---|---|
| Alternate Names | |
| bHLHa14; HATH1; MATH-1; ATH1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ATOH1 |
| Entrez Gene ID | 474 |
| Ensemble Gene ID | ENSG00000172238 |
| RefSeq Protein Accession(s) | NP_005163.1 |
| RefSeq mRNA Accession(s) | NM_005172.1 |
| UniProt ID(s) | Q92858 |
| UniGene ID(s) | Hs.532680 |
| HGNC ID(s) | HGNC:797 |
| COSMIC ID Link(s) | ATOH1 |
| KEGG Gene ID(s) | hsa:474 |
| PharmGKB ID(s) | PA25095 |
| General Description of Recombinant Human Protein atonal homolog 1 Protein. | |
| Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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