PDF DatasheetHuman UBE2F Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant UBE2F based upon sequence from: Human
Host: QP7958 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) UBE2F, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7958.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Arg185
Amino Acid Sequence: MLTLASKLKR DDGLKGSRTA ATASDSTRRV SVRDKLLVKE VAELEANLPC TCKVHFPDPN KLHCFQLTVT PDEGYYQGGK FQFETEVPDA YNMVPPKVKC LTKIWHPNIT ETGEICLSLL REHSIDGTGW APTRTLKDVV WGLNSLFTDL LNFDDPLNIE AAEHHLRDKE DFRNKVDDYI KRYAR
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human UBE2F Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human UBE2F Protein General Information | |
|---|---|
| Alternate Names | |
| UBE2F; NCE2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | UBE2F |
| Entrez Gene ID | 140739 |
| Ensemble Gene ID | ENSG00000184182 |
| RefSeq Protein Accession(s) | NP_001265234.1 |
| RefSeq mRNA Accession(s) | NM_001278305.1, NM_001278306.1, NM_001278307.1, NM_001278308.1, NM_080678.2 |
| UniProt ID(s) | Q969M7 |
| UniGene ID(s) | Hs.471785 |
| HGNC ID(s) | HGNC:12480 |
| COSMIC ID Link(s) | UBE2F |
| KEGG Gene ID(s) | hsa:140739 |
| PharmGKB ID(s) | PA37130 |
| General Description of Recombinant Human UBE2F Protein. | |
| Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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