PDF DatasheetHuman SOSS complex subunit B2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant SOSS complex subunit B2 based upon sequence from: Human
Host: QP7959 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) SOSS complex subunit B2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7959.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Arg204
Amino Acid Sequence: MNRVNDPLIF IRDIKPGLKN LNVVFIVLEI GRVTKTKDGH EVRSCKVADK TGSITISVWD EIGGLIQPGD IIRLTRGYAS MWKGCLTLYT GRGGELQKIG EFCMVYSEVP NFSEPNPDYR GQQNKGAQSE QKNNSMNSNM GTGTFGPVGN GVHTGPESRE HQFSHAGRSN GRGLINPQLQ GTASNQTVMT TISNGRDPRR AFKR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human SOSS complex subunit B2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human SOSS complex subunit B2 Protein General Information | |
|---|---|
| Alternate Names | |
| SOSS-B2; OBFC2A; SSB2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NABP1 |
| Entrez Gene ID | 64859 |
| Ensemble Gene ID | ENSG00000173559 |
| RefSeq Protein Accession(s) | NP_001026886.1 |
| RefSeq mRNA Accession(s) | NM_001031716.2, NM_001254736.1, XM_017004722.1 |
| UniProt ID(s) | Q96AH0 |
| UniGene ID(s) | Hs.591610 |
| HGNC ID(s) | HGNC:26232 |
| KEGG Gene ID(s) | hsa:64859 |
| PharmGKB ID(s) | PA143485566 |
| General Description of Recombinant Human SOSS complex subunit B2 Protein. | |
| Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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