PDF DatasheetHuman Carbonyl reductase family member 4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Carbonyl reductase family member 4 based upon sequence from: Human
Host: QP7969 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Carbonyl reductase family member 4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7969.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Leu237
Amino Acid Sequence: MDKVCAVFGG SRGIGRAVAQ LMARKGYRLA VIARNLEGAK AAAGDLGGDH LAFSCDVAKE HDVQNTFEEL EKHLGRVNFL VNAAGINRDG LLVRTKTEDM VSQLHTNLLG SMLTCKAAMR TMIQQQGGSI VNVGSIVGLK GNSGQSVYSA SKGGLVGFSR ALAKEVARKK IRVNVVAPGF VHTDMTKDLK EEHLKKNIPL GRFGETIEVA HAVVFLLESP YITGHVLVVD GGLQLIL
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Carbonyl reductase family member 4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Carbonyl reductase family member 4 Protein General Information | |
|---|---|
| Alternate Names | |
| SDR45C1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CBR4 |
| Entrez Gene ID | 84869 |
| Ensemble Gene ID | ENSG00000145439 |
| RefSeq Protein Accession(s) | NP_116172.2 |
| RefSeq mRNA Accession(s) | NM_032783.4 |
| UniProt ID(s) | Q8N4T8 |
| UniGene ID(s) | Hs.659311 |
| HGNC ID(s) | HGNC:25891 |
| COSMIC ID Link(s) | CBR4 |
| KEGG Gene ID(s) | hsa:84869 |
| PharmGKB ID(s) | PA144596471 |
| General Description of Recombinant Human Carbonyl reductase family member 4 Protein. | |
| The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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