PDF DatasheetHuman C-type lectin domain family 4 member C Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant C-type lectin domain family 4 member C based upon sequence from: Human
Host: QP7991 protein expressed in E.coli, Yeast, Mammal..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) C-type lectin domain family 4 member C, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7991.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Asn45 – Ile213
Amino Acid Sequence: NFMYSKTVKR LSKLREYQQY HPSLTCVMEG KDIEDWSCCP TPWTSFQSSC YFISTGMQSW TKSQKNCSVM GADLVVINTR EEQDFIIQNL KRNSSYFLGL SDPGGRRHWQ WVDQTPYNEN VTFWHSGEPN NLDERCAIIN FRSSEEWGWN DIHCHVPQKS ICKMKKIYI
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human C-type lectin domain family 4 member C Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human C-type lectin domain family 4 member C Protein General Information | |
|---|---|
| Alternate Names | |
| CD303; HECL; BDCA2; CLECSF11; CLECSF7; DLEC; PRO34150 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CLEC4C |
| Entrez Gene ID | 170482 |
| Ensemble Gene ID | ENSG00000198178 |
| RefSeq Protein Accession(s) | NP_569708.1 |
| RefSeq mRNA Accession(s) | NM_130441.2, NM_203503.1 |
| UniProt ID(s) | Q8WTT0 |
| UniGene ID(s) | Hs.351812 |
| HGNC ID(s) | HGNC:13258 |
| COSMIC ID Link(s) | CLEC4C |
| KEGG Gene ID(s) | hsa:170482 |
| PharmGKB ID(s) | PA26585 |
| General Description of Recombinant Human C-type lectin domain family 4 member C Protein. | |
| Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not se to bind mannose. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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