PDF DatasheetHuman Hermansky-Pudlak syndrome 1 protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Hermansky-Pudlak syndrome 1 protein based upon sequence from: Human
Host: QP7996 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Hermansky-Pudlak syndrome 1 protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7996.
Bioactivity Data: Untested
Full Length? Full Length of Isoform III
Expression Region: Met1 – Ser324
Amino Acid Sequence: MKCVLVATEG AEVLFYWTDQ EFEESLRLKF GQSENEEEEL PALEDQLSTL LAPVIISSMT MLEKLSDTYT CFSTENGNFL YVLHLFGECL FIAINGDHTE SEGDLRRKLY VLKYLFEVHF GLVTVDGHLI RKELRPPDLA QRVQLWEHFQ SLLWTYSRLR EQEQCFAVEA LERLIHPQLC ELCIEALERH VIQAVNTSPE RGGEEALHAF LLVHSKLLAF YSSHSASSLR PADLLALILL VQDLYPSEST AEDDIQPSPR RARSSQNIPV QQAWSPHSTG PTGGSSAETE TDSFSLPEEY FTPAPSPGDQ SSGEDRRKAG GNNS
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Hermansky-Pudlak syndrome 1 protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Hermansky-Pudlak syndrome 1 protein Protein General Information | |
|---|---|
| Alternate Names | |
| HPS; BLOC3S1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HPS1 |
| Entrez Gene ID | 3257 |
| Ensemble Gene ID | ENSG00000107521 |
| RefSeq Protein Accession(s) | NP_000186.2 |
| RefSeq mRNA Accession(s) | NM_000195.4, NM_001322476.1, NM_001322477.1, NM_001322478.1, NM_001322479.1, NM_182639.3, XM_005269757.4 |
| UniProt ID(s) | Q92902 |
| UniGene ID(s) | Hs.404568 |
| HGNC ID(s) | HGNC:5163 |
| COSMIC ID Link(s) | HPS1 |
| KEGG Gene ID(s) | hsa:3257 |
| PharmGKB ID(s) | PA35101 |
| General Description of Recombinant Human Hermansky-Pudlak syndrome 1 protein Protein. | |
| Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38 | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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