PDF DatasheetHuman Docking protein 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Docking protein 1 based upon sequence from: Human
Host: QP8017 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Docking protein 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8017.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Thr481
Amino Acid Sequence: MDGAVMEGPL FLQSQRFGTK RWRKTWAVLY PASPHGVARL EFFDHKGSSS GGGRGSSRRL DCKVIRLAEC VSVAPVTVET PPEPGATAFR LDTAQRSHLL AADAPSSAAW VQTLCRNAFP KGSWTLAPTD NPPKLSALEM LENSLYSPTW EGSQFWVTVQ RTEAAERCGL HGSYVLRVEA ERLTLLTVGA QSQILEPLLS WPYTLLRRYG RDKVMFSFEA GRRCPSGPGT FTFQTAQGND IFQAVETAIH RQKAQGKAGQ GHDVLRADSH EGEVAEGKLP SPPGPQELLD SPPALYAEPL DSLRIAPCPS QDSLYSDPLD STSAQAGEGV QRKKPLYWDL YEHAQQQLLK AKLTDPKEDP IYDEPEGLAP VPPQGLYDLP REPKDAWWCQ ARVKEEGYEL PYNPATDDYA VPPPRSTKPL LAPKPQGPAF PEPGTATGSG IKSHNSALYS QVQKSGASGS WDCGLSRVGT DKTGVKSEGS T
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Docking protein 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Docking protein 1 Protein General Information | |
|---|---|
| Alternate Names | |
| P62DOK; pp62 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DOK1 |
| Entrez Gene ID | 1796 |
| Ensemble Gene ID | ENSG00000115325 |
| RefSeq Protein Accession(s) | NP_001184189.1 |
| RefSeq mRNA Accession(s) | NM_001197260.1, NM_001318868.1, NM_001381.4 |
| UniProt ID(s) | Q99704 |
| UniGene ID(s) | Hs.103854 |
| HGNC ID(s) | HGNC:2990 |
| COSMIC ID Link(s) | DOK1 |
| KEGG Gene ID(s) | hsa:1796 |
| PharmGKB ID(s) | PA27456 |
| General Description of Recombinant Human Docking protein 1 Protein. | |
| DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assbly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.