PDF DatasheetHuman Methionine synthase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Methionine synthase based upon sequence from: Human
Host: QP8028 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Methionine synthase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8028.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser923 – Asp1265
Amino Acid Sequence: SLKERRYLPL SQARKSGFQM DWLSEPHPVK PTFIGTQVFE DYDLQKLVDY IDWKPFFDVW QLRGKYPNRG FPKIFNDKTV GGEARKVYDD AHNMLNTLIS QKKLRARGVV GFWPAQSIQD DIHLYAEAAV PQAAEPIATF YGLRQQAEKD SASTEPYYCL SDFIAPLHSG IRDYLGLFAV ACFGVEELSK AYEDDGDDYS SIMVKALGDR LAEAFAEELH ERVRRELWAY CGSEQLDVAD LRRLRYKGIR PAPGYPSQPD HTEKLTMWRL ADIEQSTGIR LTESLAMAPA SAVSGLYFSN LKSKYFAVGK ISKDQVEDYA LRKNISVAEV EKWLGPILGY DTD
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Methionine synthase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Methionine synthase Protein General Information | |
|---|---|
| Alternate Names | |
| HMAG; MS; cblG | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MTR |
| Entrez Gene ID | 4548 |
| Ensemble Gene ID | ENSG00000116984 |
| RefSeq Protein Accession(s) | NP_000245.2 |
| RefSeq mRNA Accession(s) | NM_000254.2, NM_001291939.1, NM_001291940.1 |
| UniProt ID(s) | Q99707 |
| UniGene ID(s) | Hs.498187 |
| HGNC ID(s) | HGNC:7468 |
| COSMIC ID Link(s) | MTR |
| KEGG Gene ID(s) | hsa:4548 |
| PharmGKB ID(s) | PA31272 |
| General Description of Recombinant Human Methionine synthase Protein. | |
| Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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