Human Endoplasmic reticulum resident protein 44 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Endoplasmic reticulum resident protein 44 based upon sequence from: Human
Host: QP8042 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Endoplasmic reticulum resident protein 44, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8042.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu30 – Leu406
Amino Acid Sequence: EITSLDTENI DEILNNADVA LVNFYADWCR FSQMLHPIFE EASDVIKEEF PNENQVVFAR VDCDQHSDIA QRYRISKYPT LKLFRNGMMM KREYRGQRSV KALADYIRQQ KSDPIQEIRD LAEITTLDRS KRNIIGYFEQ KDSDNYRVFE RVANILHDDC AFLSAFGDVS KPERYSGDNI IYKPPGHSAP DMVYLGAMTN FDVTYNWIQD KCVPLVREIT FENGEELTEE GLPFLILFHM KEDTESLEIF QNEVARQLIS EKGTINFLHA DCDKFRHPLL HIQKTPADCP VIAIDSFRHM YVFGDFKDVL IPGKLKQFVF DLHSGKLHRE FHHGPDPTDT APGEQAQDVA SSPPESSFQK LAPSEYRYTL LRDRDEL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Endoplasmic reticulum resident protein 44 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human Endoplasmic reticulum resident protein 44 Protein General Information | |
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Alternate Names | |
TXNDC4; PDIA10 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | ERP44 |
Entrez Gene ID | 23071 |
Ensemble Gene ID | ENSG00000023318 |
RefSeq Protein Accession(s) | NP_055866.1 |
RefSeq mRNA Accession(s) | NM_015051.2 |
UniProt ID(s) | Q9BS26 |
UniGene ID(s) | Hs.154023 |
HGNC ID(s) | HGNC:18311 |
COSMIC ID Link(s) | ERP44 |
KEGG Gene ID(s) | hsa:23071 |
PharmGKB ID(s) | PA164719295 |
General Description of Recombinant Human Endoplasmic reticulum resident protein 44 Protein. | |
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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