PDF DatasheetHuman Programmed cell death protein 10 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Programmed cell death protein 10 based upon sequence from: Human
Host: QP8043 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Programmed cell death protein 10, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8043.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ala212
Amino Acid Sequence: MRMTMEEMKN EAETTSMVSM PLYAVMYPVF NELERVNLSA AQTLRAAFIK AEKENPGLTQ DIIMKILEKK SVEVNFTESL LRMAADDVEE YMIERPEPEF QDLNEKARAL KQILSKIPDE INDRVRFLQT IKDIASAIKE LLDTVNNVFK KYQYQNRRAL EHQKKEFVKY SKSFSDTLKT YFKDGKAINV FVSANRLIHQ TNLILQTFKT VA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Programmed cell death protein 10 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Programmed cell death protein 10 Protein General Information | |
|---|---|
| Alternate Names | |
| CCM3; TFAR15 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PDCD10 |
| Entrez Gene ID | 11235 |
| Ensemble Gene ID | ENSG00000114209 |
| RefSeq Protein Accession(s) | NP_009148.2 |
| RefSeq mRNA Accession(s) | NM_007217.3, NM_145859.1, NM_145860.1, XM_005247086.4, XM_005247087.4, XM_005247088.3, XM_006713485.3, XM_011512368.2, XM_011512369.2, XM_017005644.1 |
| UniProt ID(s) | Q9BUL8 |
| UniGene ID(s) | Hs.478150 |
| HGNC ID(s) | HGNC:8761 |
| COSMIC ID Link(s) | PDCD10 |
| KEGG Gene ID(s) | hsa:11235 |
| PharmGKB ID(s) | PA33111 |
| General Description of Recombinant Human Programmed cell death protein 10 Protein. | |
| Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assbly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hatopoiesis during bryonic development . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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