PDF DatasheetHuman AKT-interacting protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant AKT-interacting protein based upon sequence from: Human
Host: QP8053 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) AKT-interacting protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8053.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Thr292
Amino Acid Sequence: MNPFWSMSTS SVRKRSEGEE KTLTGDVKTS PPRTAPKKQL PSIPKNALPI TKPTSPAPAA QSTNGTHASY GPFYLEYSLL AEFTLVVKQK LPGVYVQPSY RSALMWFGVI FIRHGLYQDG VFKFTVYIPD NYPDGDCPRL VFDIPVFHPL VDPTSGELDV KRAFAKWRRN HNHIWQVLMY ARRVFYKIDT ASPLNPEAAV LYEKDIQLFK SKVVDSVKVC TARLFDQPKI EDPYAISFSP WNPSVHDEAR EKMLTQKKPE EQHNKSVHVA GLSWVKPGSV QPFSKEEKTV AT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human AKT-interacting protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human AKT-interacting protein Protein General Information | |
|---|---|
| Alternate Names | |
| FT1; FTS | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | AKTIP |
| Entrez Gene ID | 64400 |
| Ensemble Gene ID | ENSG00000166971 |
| RefSeq Protein Accession(s) | NP_001012398.1 |
| RefSeq mRNA Accession(s) | NM_001012398.2, NM_001308325.1, NM_022476.3, XM_005256095.4, XM_005256096.4, XM_005256097.4, XM_005256098.4, XM_017023564.1, XM_017023565.1, XM_017023566.1 |
| UniProt ID(s) | Q9H8T0 |
| UniGene ID(s) | Hs.380897 |
| HGNC ID(s) | HGNC:16710 |
| COSMIC ID Link(s) | AKTIP |
| KEGG Gene ID(s) | hsa:64400 |
| PharmGKB ID(s) | PA162376210 |
| General Description of Recombinant Human AKT-interacting protein Protein. | |
| Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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