PDF DatasheetHuman Plexin-A4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Plexin-A4 based upon sequence from: Human
Host: QP8056 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Plexin-A4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8056.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Thr24 – Ser522
Amino Acid Sequence: TLLTRQPAPL SQKQRSFVTF RGEPAEGFNH LVVDERTGHI YLGAVNRIYK LSSDLKVLVT HETGPDEDNP KCYPPRIVQT CNEPLTTTNN VNKMLLIDYK ENRLIACGSL YQGICKLLRL EDLFKLGEPY HKKEHYLSGV NESGSVFGVI VSYSNLDDKL FIATAVDGKP EYFPTISSRK LTKNSEADGM FAYVFHDEFV ASMIKIPSDT FTIIPDFDIY YVYGFSSGNF VYFLTLQPEM VSPPGSTTKE QVYTSKLVRL CKEDTAFNSY VEVPIGCERS GVEYRLLQAA YLSKAGAVLG RTLGVHPDDD LLFTVFSKGQ KRKMKSLDES ALCIFILKQI NDRIKERLQS CYRGEGTLDL AWLKVKDIPC SSALLTIDDN FCGLDMNAPL GVSDMVRGIP VFTEDRDRMT SVIAYVYKNH SLAFVGTKSG KLKKIRVDGP RGNALQYETV QVVDPGPVLR DMAFSKDHEQ LYIMSERQLT RVPVESCGQY QSCGECLGS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Plexin-A4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Plexin-A4 Protein General Information | |
|---|---|
| Alternate Names | |
| FAYV2820; PLXNA4B; PRO34003; PLXNA4A; PLEXA4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PLXNA4 |
| Entrez Gene ID | 91584 |
| Ensemble Gene ID | ENSG00000221866 |
| RefSeq Protein Accession(s) | NP_001099013.1 |
| RefSeq mRNA Accession(s) | NM_001105543.1, NM_020911.1, NM_181775.3, XM_005250686.4, XM_006716171.3 |
| UniProt ID(s) | Q9HCM2 |
| UniGene ID(s) | Hs.511454 |
| HGNC ID(s) | HGNC:9102 |
| COSMIC ID Link(s) | PLXNA4 |
| KEGG Gene ID(s) | hsa:91584 |
| PharmGKB ID(s) | PA162399757 |
| General Description of Recombinant Human Plexin-A4 Protein. | |
| Coreceptor for SA3A. Necessary for signaling by class 3 saphorins and subsequent rodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous syst. Class 3 saphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific saphorins, and its Cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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