PDF DatasheetHuman Dual specificity protein phosphatase 26 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Dual specificity protein phosphatase 26 based upon sequence from: Human
Host: QP8061 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Dual specificity protein phosphatase 26, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8061.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ala211
Amino Acid Sequence: MCPGNWLWAS MTFMARFSRS SSRSPVRTRG TLEEMPTVQH PFLNVFELER LLYTGKTACN HADEVWPGLY LGDQDMANNR RELRRLGITH VLNASHSRWR GTPEAYEGLG IRYLGVEAHD SPAFDMSIHF QTAADFIHRA LSQPGGKILV HCAVGVSRSA TLVLAYLMLY HHLTLVEAIK KVKDHRGIIP NRGFLRQLLA LDRRLRQGLE A
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Dual specificity protein phosphatase 26 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Dual specificity protein phosphatase 26 Protein General Information | |
|---|---|
| Alternate Names | |
| LDP-4; NATA1; SKRP3; MKP-8; DSP-4; DUSP24; MKP8; NEAP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DUSP26 |
| Entrez Gene ID | 78986 |
| Ensemble Gene ID | ENSG00000133878 |
| RefSeq Protein Accession(s) | NP_001292044.1 |
| RefSeq mRNA Accession(s) | NM_001305115.1, NM_001305116.1, NM_024025.2 |
| UniProt ID(s) | Q9BV47 |
| UniGene ID(s) | Hs.8719 |
| HGNC ID(s) | HGNC:28161 |
| COSMIC ID Link(s) | DUSP26 |
| KEGG Gene ID(s) | hsa:78986 |
| PharmGKB ID(s) | PA142671921 |
| General Description of Recombinant Human Dual specificity protein phosphatase 26 Protein. | |
| Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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