PDF DatasheetHuman IL37 / IL1F7 / IL-1H4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL37 / IL1F7 / IL-1H4 based upon sequence from: Human
Host: QP8077 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) IL37 / IL1F7 / IL-1H4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8077.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: VHTSPKVKNL NPKKFSIHDQ DHKVLVLDSG NLIAVPDKNY IRPEIFFALA SSLSSASAEK GSPILLGVSK GEFCLYCDKD KGQSHPSLQL KKEKLMKLAA QKESARRPFI FYRAQVGSWN MLESAAHPGW FICTSCNCNE PVGVTDKFEN RKHIEFSFQP VCKAEMSPSE VSD
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IL37 / IL1F7 / IL-1H4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IL37 / IL1F7 / IL-1H4 Protein General Information | |
|---|---|
| Alternate Names | |
| IL37; IL1F7; IL-1H4; IL-1RP1; IL1RP1; IL-1F7; FIL1(ZETA); IL1F7; IL-37; FIL1; FIL1Z; IL-1H; IL1H4; IL-1H4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL37 |
| Entrez Gene ID | 27178 |
| Ensemble Gene ID | ENSG00000125571 |
| RefSeq Protein Accession(s) | NP_055254.2 |
| RefSeq mRNA Accession(s) | NM_014439.3, NM_173202.1, NM_173203.1, NM_173204.1, NM_173205.1, XM_011510963.2, XM_011510964.2 |
| UniProt ID(s) | Q9NZH6 |
| UniGene ID(s) | Hs.166371 |
| HGNC ID(s) | HGNC:15563 |
| COSMIC ID Link(s) | IL37 |
| KEGG Gene ID(s) | hsa:27178 |
| PharmGKB ID(s) | PA38390 |
| General Description of Recombinant Human IL37 / IL1F7 / IL-1H4 Protein. | |
| Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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