PDF DatasheetMouse CLEC4E / CLECSF9 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CLEC4E / CLECSF9 based upon sequence from: Mouse
Host: QP8099 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) CLEC4E / CLECSF9, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8099.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Thr46 – Asp214
Amino Acid Sequence: TYRSSQISGQ NLQPHRNIKE LSCYSEASGS VKNCCPLNWK HYQSSCYFFS TTTLTWSSSL KNCSDMGAHL VVIDTQEEQE FLFRTKPKRK EFYIGLTDQV VEGQWQWVDD TPFTESLSFW DAGEPNNIVL VEDCATIRDS SNSRKNWNDI PCFYSMPWIC EMPEISPLD
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse CLEC4E / CLECSF9 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse CLEC4E / CLECSF9 Protein General Information | |
|---|---|
| Alternate Names | |
| CLEC4E; CLECSF9; EGK_03329 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Clec4e |
| Entrez Gene ID | 56619 |
| Ensemble Gene ID | ENSMUSG00000030142 |
| RefSeq Protein Accession(s) | NP_064332.1 |
| RefSeq mRNA Accession(s) | NM_019948.2 |
| UniProt ID(s) | Q9R0Q8 |
| UniGene ID(s) | Mm.248327 |
| COSMIC ID Link(s) | Clec4e |
| KEGG Gene ID(s) | mmu:56619 |
| General Description of Recombinant Mouse CLEC4E / CLECSF9 Protein. | |
| C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6′-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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