PDF DatasheetHuman GLO1 / Glyoxalase 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant GLO1 / Glyoxalase 1 based upon sequence from: Human
Host: QP8110 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) GLO1 / Glyoxalase 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8110.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Met184
Amino Acid Sequence: MAEPQPPSGG LTDEAALSCC SDADPSTKDF LLQQTMLRVK DPKKSLDFYT RVLGMTLIQK CDFPIMKFSL YFLAYEDKND IPKEKDEKIA WALSRKATLE LTHNWGTEDD ETQSYHNGNS DPRGFGHIGI AVPDVYSACK RFEELGVKFV KKPDDGKMKG LAFIQDPDGY WIEILNPNKM ATLM
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GLO1 / Glyoxalase 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human GLO1 / Glyoxalase 1 Protein General Information | |
|---|---|
| Alternate Names | |
| GLO1; Glyoxalase 1; AW550643; GLY1; Glo-1r; 2510049H23Rik; Glo-1; Glo-1s; Glo1-r; 0610009E22Rik; Glo1-s; 1110008E19Rik; Qglo | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GLO1 |
| Entrez Gene ID | 2739 |
| Ensemble Gene ID | ENSG00000124767 |
| RefSeq Protein Accession(s) | NP_006699.2 |
| RefSeq mRNA Accession(s) | NM_006708.2 |
| UniProt ID(s) | Q04760 |
| UniGene ID(s) | Hs.268849 |
| HGNC ID(s) | HGNC:4323 |
| COSMIC ID Link(s) | GLO1 |
| KEGG Gene ID(s) | hsa:2739 |
| PharmGKB ID(s) | PA28724 |
| General Description of Recombinant Human GLO1 / Glyoxalase 1 Protein. | |
| Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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