PDF DatasheetHuman MICOS complex subunit MIC19 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant MICOS complex subunit MIC19 based upon sequence from: Human
Host: QP8122 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) MICOS complex subunit MIC19, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8122.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: MGGTTSTRRV TFEADENENI TVVKGIRLSE NVIDRMKESS PSGSKSQRYS GAYGASVSDE ELKRRVAEEL ALEQAKKESE DQKRLKQAKE LDRERAAANE QLTRAILRER ICSEEERAKA KHLARQLEEK DRVLKKQDAF YKEQLARLEE RSSEFYRVTT EQYQKAAEEV EAKFKRYESH PVCADLQAKI LQCYRENTHQ TLKCSALATQ YMHCVNHAKQ SMLEKGG
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human MICOS complex subunit MIC19 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human MICOS complex subunit MIC19 Protein General Information | |
|---|---|
| Alternate Names | |
| Mic19; PPP1R22; MINOS3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CHCHD3 |
| Entrez Gene ID | 54927 |
| Ensemble Gene ID | ENSG00000106554 |
| RefSeq Protein Accession(s) | NP_001304106.1 |
| RefSeq mRNA Accession(s) | NM_001317177.1, NM_017812.3 |
| UniProt ID(s) | Q9NX63 |
| UniGene ID(s) | Hs.655010 |
| HGNC ID(s) | HGNC:21906 |
| COSMIC ID Link(s) | CHCHD3 |
| KEGG Gene ID(s) | hsa:54927 |
| PharmGKB ID(s) | PA134983108 |
| General Description of Recombinant Human MICOS complex subunit MIC19 Protein. | |
| Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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