PDF DatasheetHuman GMP reductase 2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant GMP reductase 2 based upon sequence from: Human
Isoform: Isoform 2
Host: QP8126 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) GMP reductase 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8126.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 2
Expression Region: Met1 – Cys366
Amino Acid Sequence: MTSCLPALRF IATPRLSAMP HIDNDVKLDF KDVLLRPKRS TLKSRSEVDL TRSFSFRNSK QTYSGVPIIA ANMDTVGTFE MAKVLCKFSL FTAVHKHYSL VQWQEFAGQN PDCLEHLAAS SGTGSSDFEQ LEQILEAIPQ VKYICLDVAN GYSEHFVEFV KDVRKRFPQH TIMAGNVVTG EMVEELILSG ADIIKVGIGP GSVCTTRKKT GVGYPQLSAV MECADAAHGL KGHIISDGGC SCPGDVAKAF GAGADFVMLG GMLAGHSESG GELIERDGKK YKLFYGMSSE MAMKKYAGGV AEYRASEGKT VEVPFKGDVE HTIRDILGGI RSTCTYVGAA KLKELSRRTT FIRVTQQVNP IFSEAC
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GMP reductase 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human GMP reductase 2 Protein General Information | |
|---|---|
| Alternate Names | |
| GMPR 2 | |
| Molecular Weight | |
| Isoform 2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GMPR2 |
| Entrez Gene ID | 51292 |
| Ensemble Gene ID | ENSG00000100938 |
| RefSeq Protein Accession(s) | NP_001002000.1 |
| RefSeq mRNA Accession(s) | NM_001002000.2, NM_001002001.2, NM_001002002.2, NM_001283021.1, NM_001283022.1, NM_001283023.1, NM_016576.4 |
| UniProt ID(s) | Q9P2T1 |
| UniGene ID(s) | Hs.368855 |
| HGNC ID(s) | HGNC:4377 |
| COSMIC ID Link(s) | GMPR2 |
| KEGG Gene ID(s) | hsa:51292 |
| PharmGKB ID(s) | PA28762 |
| General Description of Recombinant Human GMP reductase 2 Protein. | |
| Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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