PDF DatasheetMouse IL1RL2 / IL-1Rrp2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL1RL2 / IL-1Rrp2 based upon sequence from: Mouse
Host: QP8137 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) IL1RL2 / IL-1Rrp2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8137.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Asp22 – Arg338
Amino Acid Sequence: DTCEDIFMHN VIISEGQPFP FNCTYPPETN GAVNLTWYKT PSKSPVSNNR HLRVHQDQTW ILFLPLTLED SGIYQCVIRN AHNCYQIAVN LTVLKNHWCD SSMEGSPVNS PDVYQQILPI GKSGSLNCHL YFPESCALDS IKWYKGCEEI KAGKKYSPSG AKLLVNNVAV EDGGSYACSA RLTHLGRHFT IRNYIAVNTK EVEYGRRIPN ITYPKNNSIE VPLGSTLIVN CNITDTKENT NLRCWRVNNT LVDDYYKDSK RIQEGIETNV SLRDQIRYTV NITFLKVKME DYGRPFTCHA GVSAAYIILI YPVPDFR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse IL1RL2 / IL-1Rrp2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse IL1RL2 / IL-1Rrp2 Protein General Information | |
|---|---|
| Alternate Names | |
| IL1RL2; IL-1Rrp2; IL1R-rp2; IL-1Rrp2; IL1RRP2; IL-36R | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Il1rl2 |
| Entrez Gene ID | 107527 |
| Ensemble Gene ID | ENSMUSG00000070942 |
| RefSeq Protein Accession(s) | NP_573456.1 |
| RefSeq mRNA Accession(s) | NM_133193.3, XM_006495608.3, XM_006495609.3, XM_006495610.3, XM_006495611.3 |
| UniProt ID(s) | Q9ERS7 |
| UniGene ID(s) | Mm.155583 |
| COSMIC ID Link(s) | Il1rl2 |
| KEGG Gene ID(s) | mmu:107527 |
| General Description of Recombinant Mouse IL1RL2 / IL-1Rrp2 Protein. | |
| Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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