PDF DatasheetHuman S100A14 / S114 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant S100A14 / S114 based upon sequence from: Human
Host: QP8145 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) S100A14 / S114, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8145.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – His104
Amino Acid Sequence: MGQCRSANAE DAQEFSDVER AIETLIKNFH QYSVEGGKET LTPSELRDLV TQQLPHLMPS NCGLEEKIAN LGSCNDSKLE FRSFWELIGE AAKSVKLERP VRGH
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human S100A14 / S114 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human S100A14 / S114 Protein General Information | |
|---|---|
| Alternate Names | |
| S100A14; S114; BCMP84; S100A15 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | S100A14 |
| Entrez Gene ID | 57402 |
| Ensemble Gene ID | ENSG00000189334 |
| RefSeq Protein Accession(s) | NP_065723.1 |
| RefSeq mRNA Accession(s) | NM_020672.2, XM_005245362.1, XM_017001875.1 |
| UniProt ID(s) | Q9HCY8 |
| UniGene ID(s) | Hs.288998 |
| HGNC ID(s) | HGNC:18901 |
| COSMIC ID Link(s) | S100A14 |
| KEGG Gene ID(s) | hsa:57402 |
| PharmGKB ID(s) | PA134905502 |
| General Description of Recombinant Human S100A14 / S114 Protein. | |
| Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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