Human OSGEP Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant OSGEP based upon sequence from: Human
Host: QP8150 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) OSGEP, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8150.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Asp335
Amino Acid Sequence: MPAVLGFEGS ANKIGVGVVR DGKVLANPRR TYVTPPGTGF LPGDTARHHR AVILDLLQEA LTESGLTSQD IDCIAYTKGP GMGAPLVSVA VVARTVAQLW NKPLVGVNHC IGHIEMGRLI TGATSPTVLY VSGGNTQVIA YSEHRYRIFG ETIDIAVGNC LDRFARVLKI SNDPSPGYNI EQMAKRGKKL VELPYTVKGM DVSFSGILSF IEDVAHRMLA TGECTPEDLC FSLQETVFAM LVEITERAMA HCGSQEALIV GGVGCNVRLQ EMMATMCQER GARLFATDER FCIDNGAMIA QAGWEMFRAG HRTPLSDSGV TQRYRTDEVE VTWRD
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human OSGEP Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human OSGEP Protein General Information | |
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Alternate Names | |
GCPL1; OSGEP1; PRSMG1; KAE1; Probable tRNA N6-adenosine threonylcarbamoyltransfera | |
Curated Database and Bioinformatic Data | |
Gene Symbol | OSGEP |
Entrez Gene ID | 55644 |
Ensemble Gene ID | ENSG00000092094 |
RefSeq Protein Accession(s) | NP_060277.1 |
RefSeq mRNA Accession(s) | NM_017807.3 |
UniProt ID(s) | Q9NPF4 |
UniGene ID(s) | Hs.525196 |
HGNC ID(s) | HGNC:18028 |
COSMIC ID Link(s) | OSGEP |
KEGG Gene ID(s) | hsa:55644 |
PharmGKB ID(s) | PA32834 |
General Description of Recombinant Human OSGEP Protein. | |
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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