Human E3 ubiquitin-protein ligase TRIM9 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant E3 ubiquitin-protein ligase TRIM9 based upon sequence from: Human
Isoform: Isoform 5
Host: QP8167 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) E3 ubiquitin-protein ligase TRIM9, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8167.
Bioactivity Data: Untested
Full Length? Full Length of isoform 5
Expression Region: Met1 – Ile55
Amino Acid Sequence: MEEMEEELKC PVCGSFYREP IILPCSHNLC QACARNILVQ TPESESPQSH RAAGSGVSDY DYLDLDKMSL YSEADSGYGS YGGFASAPTT PCQKSPNGVR VFPPAMPPPA THLSPALAPV PRNSCITCPQ CHRSLILDDR GLRGFPKNRV LEGVIDRYQQ SKAAALKCQL CEKAPKEATV MCEQCDVFYC DPCRLRCHPP RGPLAKHRLV PPAQGRVSRR LSPRKVSTCT DHELENHSMY CVQCKMPVCY QCLEEGKHSS HEVKALGAMW KLHKSQLSQA LNGLSDRAKE AKEFLVQLRN MVQQIQENSV EFEACLVAQC DALIDALNRR KAQLLARVNK EHEHKLKVVR DQISHCTVKL RQTTGLMEYC LEVIKENDPS GFLQISDALI RRVHLTEDQW GKGTLTPRMT TDFDLSLDNS PLLQSIHQLD FVQVKASSPV PATPILQLEE CCTHNNSATL SWKQPPLSTV PADGYILELD DGNGGQFREV YVGKETMCTV DGLHFNSTYN ARVKAFNKTG VSPYSKTLVL QTSEGKALQQ YPSERELRGI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human E3 ubiquitin-protein ligase TRIM9 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human E3 ubiquitin-protein ligase TRIM9 Protein General Information | |
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Alternate Names | |
RNF91; SPRING | |
Molecular Weight | |
Isoform 5 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | TRIM9 |
Entrez Gene ID | 114088 |
Ensemble Gene ID | ENSG00000100505 |
RefSeq Protein Accession(s) | NP_055978.4 |
RefSeq mRNA Accession(s) | NM_015163.5, NM_052978.4, XM_011536389.2, XM_017020945.1 |
UniProt ID(s) | Q9C026 |
UniGene ID(s) | Hs.654750 |
HGNC ID(s) | HGNC:16288 |
COSMIC ID Link(s) | TRIM9 |
KEGG Gene ID(s) | hsa:114088 |
PharmGKB ID(s) | PA38116 |
General Description of Recombinant Human E3 ubiquitin-protein ligase TRIM9 Protein. | |
E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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