PDF DatasheetMouse Lingo1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Lingo1 based upon sequence from: Mouse
Host: QP8168 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Lingo1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8168.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Pro37 – Thr555
Amino Acid Sequence: PPRCECSAQD RAVLCHRKRF VAVPEGIPTE TRLLDLGKNR IKTLNQDEFA SFPHLEELEL NENIVSAVEP GAFNNLFNLR TLGLRSNRLK LIPLGVFTGL SNLTKLDISE NKIVILLDYM FQDLYNLKSL EVGDNDLVYI SHRAFSGLNS LEQLTLEKCN LTSIPTEALS HLHGLIVLRL RHLNINAIRD YSFKRLYRLK VLEISHWPYL DTMTPNCLYG LNLTSLSITH CNLTAVPYLA VRHLVYLRFL NLSYNPIGTI EGSMLHELLR LQEIQLVGGQ LAVVEPYAFR GLNYLRVLNV SGNQLTTLEE SAFHSVGNLE TLILDSNPLA CDCRLLWVFR RRWRLNFNRQ QPTCATPEFV QGKEFKDFPD VLLPNYFTCR RAHIRDRKAQ QVFVDEGHTV QFVCRADGDP PPAILWLSPR KHLVSAKSNG RLTVFPDGTL EVRYAQVQDN GTYLCIAANA GGNDSMPAHL HVRSYSPDWP HQPNKTFAFI SNQPGEGEAN STRATVPFPF DIKTLIIAT
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse Lingo1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Lingo1 Protein General Information | |
|---|---|
| Alternate Names | |
| UNQ201; 4930471K13Rik; Lrrn6a; LERN1; AV148400; LINGO-1; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Lingo1 |
| Entrez Gene ID | 235402 |
| Ensemble Gene ID | ENSMUSG00000049556 |
| RefSeq Protein Accession(s) | NP_001298005.1 |
| RefSeq mRNA Accession(s) | NM_001311076.1, NM_181074.4, XM_006511088.3, XM_006511089.3, XM_006511090.3, XM_017313333.1, XM_017313334.1, XM_017313335.1, XM_017313336.1 |
| UniProt ID(s) | Q9D1T0 |
| UniGene ID(s) | Mm.246605 |
| COSMIC ID Link(s) | Lingo1 |
| KEGG Gene ID(s) | mmu:235402 |
| General Description of Recombinant Mouse Lingo1 Protein. | |
| Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination . Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.1 Publication | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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