PDF DatasheetHuman TRMT112 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant TRMT112 based upon sequence from: Human
Host: QP8188 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) TRMT112, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8188.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ser125
Amino Acid Sequence: MKLLTHNLLS SHVRGVGSRG FPLRLQATEV RICPVEFNPN FVARMIPKVE WSAFLEAADN LRLIQVPKGP VEGYEENEEF LRTMHHLLLE VEVIEGTLQC PESGRMFPIS RGIPNMLLSE EETES
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human TRMT112 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human TRMT112 Protein General Information | |
|---|---|
| Alternate Names | |
| TRMT11-2; hTrm112; HSPC170; TRM112; HSPC152; Multifunctional methyltransferase subunit TRM112-like prote | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TRMT112 |
| Entrez Gene ID | 51504 |
| Ensemble Gene ID | ENSG00000173113 |
| RefSeq Protein Accession(s) | NP_001273011.1 |
| RefSeq mRNA Accession(s) | NM_001286082.1, NM_016404.2 |
| UniProt ID(s) | Q9UI30 |
| UniGene ID(s) | Hs.333579 |
| HGNC ID(s) | HGNC:26940 |
| COSMIC ID Link(s) | TRMT112 |
| KEGG Gene ID(s) | hsa:51504 |
| PharmGKB ID(s) | PA165543757 |
| General Description of Recombinant Human TRMT112 Protein. | |
| Participates both in methylation of protein and tRNA species. The heterodimer with HK2/N6AMT1 catalyzes N5-methylation of ETF1 on ‘Gln-185’, using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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