PDF DatasheetHuman N-acetyl-D-glucosamine kinase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant N-acetyl-D-glucosamine kinase based upon sequence from: Human
Host: QP8192 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) N-acetyl-D-glucosamine kinase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8192.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Ser344
Amino Acid Sequence: AAIYGGVEGG GTRSEVLLVS EDGKILAEAD GLSTNHWLIG TDKCVERINE MVNRAKRKAG VDPLVPLRSL GLSLSGGDQE DAGRILIEEL RDRFPYLSES YLITTDAAGS IATATPDGGV VLISGTGSNC RLINPDGSES GCGGWGHMMG DEGSAYWIAH QAVKIVFDSI DNLEAAPHDI GYVKQAMFHY FQVPDRLGIL THLYRDFDKC RFAGFCRKIA EGAQQGDPLS RYIFRKAGEM LGRHIVAVLP EIDPVLFQGK IGLPILCVGS VWKSWELLKE GFLLALTQGR EIQAQNFFSS FTLMKLRHSS ALGGASLGAR HIGHLLPMDY SANAIAFYSY TFS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human N-acetyl-D-glucosamine kinase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human N-acetyl-D-glucosamine kinase Protein General Information | |
|---|---|
| Alternate Names | |
| GNK; HSA242910 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NAGK |
| Entrez Gene ID | 55577 |
| Ensemble Gene ID | ENSG00000124357 |
| RefSeq Protein Accession(s) | NP_060037.3 |
| RefSeq mRNA Accession(s) | NM_017567.4 |
| UniProt ID(s) | Q9UJ70 |
| UniGene ID(s) | Hs.7036 |
| HGNC ID(s) | HGNC:17174 |
| COSMIC ID Link(s) | NAGK |
| KEGG Gene ID(s) | hsa:55577 |
| PharmGKB ID(s) | PA31436 |
| General Description of Recombinant Human N-acetyl-D-glucosamine kinase Protein. | |
| Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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