PDF DatasheetHuman CUE domain-containing protein 2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CUE domain-containing protein 2 based upon sequence from: Human
Host: QP8197 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CUE domain-containing protein 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8197.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Ala226
Amino Acid Sequence: MELERIVSAA LLAFVQTHLP EADLSGLDEV IFSYVLGVLE DLGPSGPSEE NFDMEAFTEM MEAYVPGFAH IPRGTIGDMM QKLSGQLSDA RNKENLQPQS SGVQGQVPIS PEPLQRPEML KEETRSSAAA AADTQDEATG AEEELLPGVD VLLEVFPTCS VEQAQWVLAK ARGDLEEAVQ MLVEGKEEGP AAWEGPNQDL PRRLRGPQKD ELKSFILQKY MMVDSA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CUE domain-containing protein 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CUE domain-containing protein 2 Protein General Information | |
|---|---|
| Alternate Names | |
| bA18I14.5; C10orf66 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CUEDC2 |
| Entrez Gene ID | 79004 |
| Ensemble Gene ID | ENSG00000107874 |
| RefSeq Protein Accession(s) | NP_076945.2 |
| RefSeq mRNA Accession(s) | NM_024040.2 |
| UniProt ID(s) | Q9H467 |
| UniGene ID(s) | Hs.500874 |
| HGNC ID(s) | HGNC:28352 |
| COSMIC ID Link(s) | CUEDC2 |
| KEGG Gene ID(s) | hsa:79004 |
| PharmGKB ID(s) | PA134871975 |
| General Description of Recombinant Human CUE domain-containing protein 2 Protein. | |
| Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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